Navigating the path to distant metastasis
نویسندگان
چکیده
منابع مشابه
Navigating An Evolutionary Fast Path to Exascale – Expanded Version
Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. Approved for public release; further dissemination unlimited. NOTICE: This report was prepared as an account of work sponsore...
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Colorectal carcinoma is one of the leading causes of death in the elderly. About 20% of patients present with liver metastasis at the time of diagnosis1. The other common metastatic sites of colorectal carcinoma include the lungs, bone and brain2. Splenic metastases from colorectal carcinomas are rare and usually occur in association with other extensive metastasis3. Isolated splenic metastasis...
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BACKGROUND The formation of distant metastases constitutes a complex process with a variety of different genes and pathways involved. To improve patient survival, it is necessary to understand the underlying mechanisms of metastasis to allow for targeted intervention. METHODS This review provides an overview of the general concepts of metastasis, focusing on the most important genes and pathw...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2020
ISSN: 1061-4036,1546-1718
DOI: 10.1038/s41588-020-0660-z